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Proof Adequan® i.m. Works
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Extensive studies of Adequan® i.m. have proven it readily passes through the synovial membrane and is taken up into cartilage by diffusion. This results in the concentration and progressive accumulation of Adequan® i.m. at the site of injury. Studies have not been conducted to establish safety in breeding horses. Do not use in horses intended for human consumption.
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What is a Balanced, Healthy Joint?
What is a Diseased Joint?
Non-steroidal
anti-inflammatory drugs (NSAIDs) act rapidly and are easily administered
for the short term relief of pain
and inflammation. Potential side effects are: blood disorders, gastro-intestinal
ulcers or renal damage.
Corticosteroids are powerful anti-inflammatory
drugs that minimize pain and decrease the inflammation of soft tissue rapidly.
They can be valuable when used judiciously. Corticosteroids interrupt not
only the inflammatory process, but the repair process as well.
Sodium
hyaluronate,
often called HA, helps restore the function of the hyaluronic acid within
the joint to improve the lubrication, stimulate natural production of
HA and generally improve the synovial fluid.
Polysulfated glycosaminoglycan is a naturally-occurring complex molecule that is the essential building block of the cartilage matrix. Marketed as Adequan® i.m. (Polysulfated glycosaminoglycan), this product travels into injured joints and stimulates production of new cartilage while relieving the symptoms of non-infectious degenerative joint disease. Adequan® i.m. is the ideal, complete treatment for non-infectious degenerative joint disease. Studies have not been conducted to establish safety in breeding horses. Do not use in horses intended for human consumption. See product insert for full product information.
Many treatments are sold to relieve the symptoms of degenerative
joint disease. However, not all products are supported by solid scientific research or manufactured under approval by the U.S. Food
and Drug Administration. Those include injectable chondroitin sulfate, pharmacy-compounded injectable glucosamine, and oral products claiming to be sulfated glycosaminoglycans. Studies of non-FDA
approved products and oral nutritional supplements have shown significantly less effectiveness than products with FDA approval.
Generic products also require FDA approval since generic drugs are chemical copies of approved drugs that no longer have patent
protection. No approved generic forms of Adequan® i.m. (polysulfated glycosaminoglycan) are currently available. See product insert for full product information.
Ask your veterinarian for FDA-approved
Adequan® i.m. (polysulfated glycosaminoglycan)
If your horse exhibits heat, pain or swelling, stiffness or decreased performance, you should immediately consult your equine veterinarian.
After six weeks of comparison to intravenous Legend® (intravenous sodium hyaluronate),
Adequan® i.m. demonstrated, on average, a more rapid and
significantly better recovery:
• Decreased lameness score
• Increased stride length
• Lowered joint flexing pain score
For a full copy of this and other clinical studies, call 1-800-974-9247.
Studies have not been conducted to establish safety in breeding horses. Do not use in horses intended for human consumption.
See product insert for full product information.